Pathway Inspector: a pathway based web application for RNAseq analysis of model and non-model organisms

SUMMARY: Pathway Inspector is an easy-to-use web application helping researchers to find patterns of expression in complex RNAseq experiments. The tool combines two standard approaches for RNAseq analysis: the identification of differentially expressed genes and a topology-based analysis of enriched...

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Detalles Bibliográficos
Autores principales: Bianco, Luca, Riccadonna, Samantha, Lavezzo, Enrico, Falda, Marco, Formentin, Elide, Cavalieri, Duccio, Toppo, Stefano, Fontana, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408796/
https://www.ncbi.nlm.nih.gov/pubmed/28158604
http://dx.doi.org/10.1093/bioinformatics/btw636
Descripción
Sumario:SUMMARY: Pathway Inspector is an easy-to-use web application helping researchers to find patterns of expression in complex RNAseq experiments. The tool combines two standard approaches for RNAseq analysis: the identification of differentially expressed genes and a topology-based analysis of enriched pathways. Pathway Inspector is equipped with ad hoc interactive graphical interfaces simplifying the discovery of modulated pathways and the integration of the differentially expressed genes in the corresponding pathway topology. AVAILABILITY AND IMPLEMENTATION: Pathway Inspector is available at the website http://admiral.fmach.it/PI and has been developed in Python, making use of the Django Web Framework.

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