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INTEGRATE-neo: a pipeline for personalized gene fusion neoantigen discovery
MOTIVATION: While high-throughput sequencing (HTS) has been used successfully to discover tumor-specific mutant peptides (neoantigens) from somatic missense mutations, the field currently lacks a method for identifying which gene fusions may generate neoantigens. RESULTS: We demonstrate the applicat...
Autores principales: | Zhang, Jin, Mardis, Elaine R, Maher, Christopher A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408800/ https://www.ncbi.nlm.nih.gov/pubmed/27797777 http://dx.doi.org/10.1093/bioinformatics/btw674 |
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