MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways

SUMMARY: MetaboSignal is an R package that allows merging metabolic and signaling pathways reported in the Kyoto Encyclopaedia of Genes and Genomes (KEGG). It is a network-based approach designed to navigate through topological relationships between genes (signaling- or metabolic-genes) and metaboli...

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Detalles Bibliográficos
Autores principales: Rodriguez-Martinez, Andrea, Ayala, Rafael, Posma, Joram M, Neves, Ana L, Gauguier, Dominique, Nicholson, Jeremy K, Dumas, Marc-Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408820/
https://www.ncbi.nlm.nih.gov/pubmed/28011775
http://dx.doi.org/10.1093/bioinformatics/btw697
Descripción
Sumario:SUMMARY: MetaboSignal is an R package that allows merging metabolic and signaling pathways reported in the Kyoto Encyclopaedia of Genes and Genomes (KEGG). It is a network-based approach designed to navigate through topological relationships between genes (signaling- or metabolic-genes) and metabolites, representing a powerful tool to investigate the genetic landscape of metabolic phenotypes. AVAILABILITY AND IMPLEMENTATION: MetaboSignal is available from Bioconductor: https://bioconductor.org/packages/MetaboSignal/ SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

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