MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways

SUMMARY: MetaboSignal is an R package that allows merging metabolic and signaling pathways reported in the Kyoto Encyclopaedia of Genes and Genomes (KEGG). It is a network-based approach designed to navigate through topological relationships between genes (signaling- or metabolic-genes) and metaboli...

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Autores principales: Rodriguez-Martinez, Andrea, Ayala, Rafael, Posma, Joram M, Neves, Ana L, Gauguier, Dominique, Nicholson, Jeremy K, Dumas, Marc-Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408820/
https://www.ncbi.nlm.nih.gov/pubmed/28011775
http://dx.doi.org/10.1093/bioinformatics/btw697
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author Rodriguez-Martinez, Andrea
Ayala, Rafael
Posma, Joram M
Neves, Ana L
Gauguier, Dominique
Nicholson, Jeremy K
Dumas, Marc-Emmanuel
author_facet Rodriguez-Martinez, Andrea
Ayala, Rafael
Posma, Joram M
Neves, Ana L
Gauguier, Dominique
Nicholson, Jeremy K
Dumas, Marc-Emmanuel
author_sort Rodriguez-Martinez, Andrea
collection PubMed
description SUMMARY: MetaboSignal is an R package that allows merging metabolic and signaling pathways reported in the Kyoto Encyclopaedia of Genes and Genomes (KEGG). It is a network-based approach designed to navigate through topological relationships between genes (signaling- or metabolic-genes) and metabolites, representing a powerful tool to investigate the genetic landscape of metabolic phenotypes. AVAILABILITY AND IMPLEMENTATION: MetaboSignal is available from Bioconductor: https://bioconductor.org/packages/MetaboSignal/ SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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spelling pubmed-54088202017-05-03 MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways Rodriguez-Martinez, Andrea Ayala, Rafael Posma, Joram M Neves, Ana L Gauguier, Dominique Nicholson, Jeremy K Dumas, Marc-Emmanuel Bioinformatics Applications Notes SUMMARY: MetaboSignal is an R package that allows merging metabolic and signaling pathways reported in the Kyoto Encyclopaedia of Genes and Genomes (KEGG). It is a network-based approach designed to navigate through topological relationships between genes (signaling- or metabolic-genes) and metabolites, representing a powerful tool to investigate the genetic landscape of metabolic phenotypes. AVAILABILITY AND IMPLEMENTATION: MetaboSignal is available from Bioconductor: https://bioconductor.org/packages/MetaboSignal/ SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Oxford University Press 2017-03-01 2016-12-05 /pmc/articles/PMC5408820/ /pubmed/28011775 http://dx.doi.org/10.1093/bioinformatics/btw697 Text en © The Author 2016. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Notes
Rodriguez-Martinez, Andrea
Ayala, Rafael
Posma, Joram M
Neves, Ana L
Gauguier, Dominique
Nicholson, Jeremy K
Dumas, Marc-Emmanuel
MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways
title MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways
title_full MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways
title_fullStr MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways
title_full_unstemmed MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways
title_short MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways
title_sort metabosignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408820/
https://www.ncbi.nlm.nih.gov/pubmed/28011775
http://dx.doi.org/10.1093/bioinformatics/btw697
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