dAPE: a web server to detect homorepeats and follow their evolution

SUMMARY: Homorepeats are low complexity regions consisting of repetitions of a single amino acid residue. There is no current consensus on the minimum number of residues needed to define a functional homorepeat, nor even if mismatches are allowed. Here we present dAPE, a web server that helps follow...

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Detalles Bibliográficos
Autores principales: Mier, Pablo, Andrade-Navarro, Miguel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408840/
https://www.ncbi.nlm.nih.gov/pubmed/28031183
http://dx.doi.org/10.1093/bioinformatics/btw790
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author Mier, Pablo
Andrade-Navarro, Miguel A
author_facet Mier, Pablo
Andrade-Navarro, Miguel A
author_sort Mier, Pablo
collection PubMed
description SUMMARY: Homorepeats are low complexity regions consisting of repetitions of a single amino acid residue. There is no current consensus on the minimum number of residues needed to define a functional homorepeat, nor even if mismatches are allowed. Here we present dAPE, a web server that helps following the evolution of homorepeats based on orthology information, using a sensitive but tunable cutoff to help in the identification of emerging homorepeats. AVAILABILITY AND IMPLEMENTATION: dAPE can be accessed from http://cbdm-01.zdv.uni-mainz.de/∼munoz/polyx. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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spelling pubmed-54088402017-05-03 dAPE: a web server to detect homorepeats and follow their evolution Mier, Pablo Andrade-Navarro, Miguel A Bioinformatics Applications Notes SUMMARY: Homorepeats are low complexity regions consisting of repetitions of a single amino acid residue. There is no current consensus on the minimum number of residues needed to define a functional homorepeat, nor even if mismatches are allowed. Here we present dAPE, a web server that helps following the evolution of homorepeats based on orthology information, using a sensitive but tunable cutoff to help in the identification of emerging homorepeats. AVAILABILITY AND IMPLEMENTATION: dAPE can be accessed from http://cbdm-01.zdv.uni-mainz.de/∼munoz/polyx. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Oxford University Press 2017-04-15 2016-12-28 /pmc/articles/PMC5408840/ /pubmed/28031183 http://dx.doi.org/10.1093/bioinformatics/btw790 Text en © The Author 2016. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Applications Notes
Mier, Pablo
Andrade-Navarro, Miguel A
dAPE: a web server to detect homorepeats and follow their evolution
title dAPE: a web server to detect homorepeats and follow their evolution
title_full dAPE: a web server to detect homorepeats and follow their evolution
title_fullStr dAPE: a web server to detect homorepeats and follow their evolution
title_full_unstemmed dAPE: a web server to detect homorepeats and follow their evolution
title_short dAPE: a web server to detect homorepeats and follow their evolution
title_sort dape: a web server to detect homorepeats and follow their evolution
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408840/
https://www.ncbi.nlm.nih.gov/pubmed/28031183
http://dx.doi.org/10.1093/bioinformatics/btw790
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AT andradenavarromiguela dapeawebservertodetecthomorepeatsandfollowtheirevolution

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