Defining the clonality of peripheral T cell lymphomas using RNA-seq

MOTIVATION: In T-cell lymphoma, malignant T cells arising from a founding clone share an identical T cell receptor (TCR) and can be identified by the over-representation of this TCR relative to TCRs from the patient’s repertoire of normal T cells. Here, we demonstrate that TCR information extracted...

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Detalles Bibliográficos
Autores principales: Brown, Scott D, Hapgood, Greg, Steidl, Christian, Weng, Andrew P, Savage, Kerry J, Holt, Robert A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Discovery Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408843/
https://www.ncbi.nlm.nih.gov/pubmed/28003262
http://dx.doi.org/10.1093/bioinformatics/btw810

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