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Biomartr: genomic data retrieval with R
MOTIVATION: Retrieval and reproducible functional annotation of genomic data are crucial in biology. However, the current poor usability and transparency of retrieval methods hinders reproducibility. Here we present an open source R package, biomartr, which provides a comprehensive easy-to-use frame...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408848/ https://www.ncbi.nlm.nih.gov/pubmed/28110292 http://dx.doi.org/10.1093/bioinformatics/btw821 |
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author | Drost, Hajk-Georg Paszkowski, Jerzy |
author_facet | Drost, Hajk-Georg Paszkowski, Jerzy |
author_sort | Drost, Hajk-Georg |
collection | PubMed |
description | MOTIVATION: Retrieval and reproducible functional annotation of genomic data are crucial in biology. However, the current poor usability and transparency of retrieval methods hinders reproducibility. Here we present an open source R package, biomartr, which provides a comprehensive easy-to-use framework for automating data retrieval and functional annotation for meta-genomic approaches. The functions of biomartr achieve a high degree of clarity, transparency and reproducibility of analyses. RESULTS: The biomartr package implements straightforward functions for bulk retrieval of all genomic data or data for selected genomes, proteomes, coding sequences and annotation files present in databases hosted by the National Center for Biotechnology Information (NCBI) and European Bioinformatics Institute (EMBL-EBI). In addition, biomartr communicates with the BioMart database for functional annotation of retrieved sequences. Comprehensive documentation of biomartr functions and five tutorial vignettes provide step-by-step instructions on how to use the package in a reproducible manner. AVAILABILITY AND IMPLEMENTATION: The open source biomartr package is available at https://github.com/HajkD/biomartr and https://cran.r-project.org/web/packages/biomartr/index.html. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. |
format | Online Article Text |
id | pubmed-5408848 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-54088482017-05-03 Biomartr: genomic data retrieval with R Drost, Hajk-Georg Paszkowski, Jerzy Bioinformatics Applications Notes MOTIVATION: Retrieval and reproducible functional annotation of genomic data are crucial in biology. However, the current poor usability and transparency of retrieval methods hinders reproducibility. Here we present an open source R package, biomartr, which provides a comprehensive easy-to-use framework for automating data retrieval and functional annotation for meta-genomic approaches. The functions of biomartr achieve a high degree of clarity, transparency and reproducibility of analyses. RESULTS: The biomartr package implements straightforward functions for bulk retrieval of all genomic data or data for selected genomes, proteomes, coding sequences and annotation files present in databases hosted by the National Center for Biotechnology Information (NCBI) and European Bioinformatics Institute (EMBL-EBI). In addition, biomartr communicates with the BioMart database for functional annotation of retrieved sequences. Comprehensive documentation of biomartr functions and five tutorial vignettes provide step-by-step instructions on how to use the package in a reproducible manner. AVAILABILITY AND IMPLEMENTATION: The open source biomartr package is available at https://github.com/HajkD/biomartr and https://cran.r-project.org/web/packages/biomartr/index.html. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Oxford University Press 2017-04-15 2017-01-20 /pmc/articles/PMC5408848/ /pubmed/28110292 http://dx.doi.org/10.1093/bioinformatics/btw821 Text en © The Author 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Applications Notes Drost, Hajk-Georg Paszkowski, Jerzy Biomartr: genomic data retrieval with R |
title | Biomartr: genomic data retrieval with R |
title_full | Biomartr: genomic data retrieval with R |
title_fullStr | Biomartr: genomic data retrieval with R |
title_full_unstemmed | Biomartr: genomic data retrieval with R |
title_short | Biomartr: genomic data retrieval with R |
title_sort | biomartr: genomic data retrieval with r |
topic | Applications Notes |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408848/ https://www.ncbi.nlm.nih.gov/pubmed/28110292 http://dx.doi.org/10.1093/bioinformatics/btw821 |
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