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Genome Editing and Directed Differentiation of hPSCs for Interrogating Lineage Determinants in Human Pancreatic Development

Interrogating gene function in self-renewing or differentiating human pluripotent stem cells (hPSCs) offers a valuable platform towards understanding human development and dissecting disease mechanisms in a dish. To capitalize on this potential application requires efficient genome-editing tools to...

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Detalles Bibliográficos
Autores principales:	Shi, Zhong-Dong, Soh, Chew-Li, Zhu, Zengrong, Huangfu, Danwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MyJove Corporation 2017
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408939/ https://www.ncbi.nlm.nih.gov/pubmed/28287608 http://dx.doi.org/10.3791/55267

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