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The International College of Neuropsychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 1: Background and Methods of the Development of Guidelines

BACKGROUND: This paper includes a short description of the important clinical aspects of Bipolar Disorder with emphasis on issues that are important for the therapeutic considerations, including mixed and psychotic features, predominant polarity, and rapid cycling as well as comorbidity. METHODS: Th...

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Autores principales: Fountoulakis, Konstantinos N., Young, Allan, Yatham, Lakshmi, Grunze, Heinz, Vieta, Eduard, Blier, Pierre, Moeller, Hans Jurgen, Kasper, Siegfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408969/
https://www.ncbi.nlm.nih.gov/pubmed/27815414
http://dx.doi.org/10.1093/ijnp/pyw091
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author Fountoulakis, Konstantinos N.
Young, Allan
Yatham, Lakshmi
Grunze, Heinz
Vieta, Eduard
Blier, Pierre
Moeller, Hans Jurgen
Kasper, Siegfried
author_facet Fountoulakis, Konstantinos N.
Young, Allan
Yatham, Lakshmi
Grunze, Heinz
Vieta, Eduard
Blier, Pierre
Moeller, Hans Jurgen
Kasper, Siegfried
author_sort Fountoulakis, Konstantinos N.
collection PubMed
description BACKGROUND: This paper includes a short description of the important clinical aspects of Bipolar Disorder with emphasis on issues that are important for the therapeutic considerations, including mixed and psychotic features, predominant polarity, and rapid cycling as well as comorbidity. METHODS: The workgroup performed a review and critical analysis of the literature concerning grading methods and methods for the development of guidelines. RESULTS: The workgroup arrived at a consensus to base the development of the guideline on randomized controlled trials and related meta-analyses alone in order to follow a strict evidence-based approach. A critical analysis of the existing methods for the grading of treatment options was followed by the development of a new grading method to arrive at efficacy and recommendation levels after the analysis of 32 distinct scenarios of available data for a given treatment option. CONCLUSION: The current paper reports details on the design, method, and process for the development of CINP guidelines for the treatment of Bipolar Disorder. The rationale and the method with which all data and opinions are combined in order to produce an evidence-based operationalized but also user-friendly guideline and a specific algorithm are described in detail in this paper.
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spelling pubmed-54089692017-05-03 The International College of Neuropsychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 1: Background and Methods of the Development of Guidelines Fountoulakis, Konstantinos N. Young, Allan Yatham, Lakshmi Grunze, Heinz Vieta, Eduard Blier, Pierre Moeller, Hans Jurgen Kasper, Siegfried Int J Neuropsychopharmacol Review BACKGROUND: This paper includes a short description of the important clinical aspects of Bipolar Disorder with emphasis on issues that are important for the therapeutic considerations, including mixed and psychotic features, predominant polarity, and rapid cycling as well as comorbidity. METHODS: The workgroup performed a review and critical analysis of the literature concerning grading methods and methods for the development of guidelines. RESULTS: The workgroup arrived at a consensus to base the development of the guideline on randomized controlled trials and related meta-analyses alone in order to follow a strict evidence-based approach. A critical analysis of the existing methods for the grading of treatment options was followed by the development of a new grading method to arrive at efficacy and recommendation levels after the analysis of 32 distinct scenarios of available data for a given treatment option. CONCLUSION: The current paper reports details on the design, method, and process for the development of CINP guidelines for the treatment of Bipolar Disorder. The rationale and the method with which all data and opinions are combined in order to produce an evidence-based operationalized but also user-friendly guideline and a specific algorithm are described in detail in this paper. Oxford University Press 2016-11-04 /pmc/articles/PMC5408969/ /pubmed/27815414 http://dx.doi.org/10.1093/ijnp/pyw091 Text en © The Author 2016. Published by Oxford University Press on behalf of CINP. http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Review
Fountoulakis, Konstantinos N.
Young, Allan
Yatham, Lakshmi
Grunze, Heinz
Vieta, Eduard
Blier, Pierre
Moeller, Hans Jurgen
Kasper, Siegfried
The International College of Neuropsychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 1: Background and Methods of the Development of Guidelines
title The International College of Neuropsychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 1: Background and Methods of the Development of Guidelines
title_full The International College of Neuropsychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 1: Background and Methods of the Development of Guidelines
title_fullStr The International College of Neuropsychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 1: Background and Methods of the Development of Guidelines
title_full_unstemmed The International College of Neuropsychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 1: Background and Methods of the Development of Guidelines
title_short The International College of Neuropsychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 1: Background and Methods of the Development of Guidelines
title_sort international college of neuropsychopharmacology (cinp) treatment guidelines for bipolar disorder in adults (cinp-bd-2017), part 1: background and methods of the development of guidelines
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408969/
https://www.ncbi.nlm.nih.gov/pubmed/27815414
http://dx.doi.org/10.1093/ijnp/pyw091
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