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A Cutoff for Age at Menarche Predicting Metabolic Syndrome in Egyptian Overweight/Obese Premenopausal Women
Previous studies showed that early age at menarche is associated with increased risk of metabolic syndrome. However, the definition of early menarche at these studies was based on background data in the communities at which these studies was carried on. The aim of this work is to determine a cutoff...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Diabetes Association
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409008/ https://www.ncbi.nlm.nih.gov/pubmed/28447441 http://dx.doi.org/10.4093/dmj.2017.41.2.146 |
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author | Elsehely, Ibrahim Abdel Hafez, Hala Ghonem, Mohammed Fathi, Ali Elzehery, Rasha |
author_facet | Elsehely, Ibrahim Abdel Hafez, Hala Ghonem, Mohammed Fathi, Ali Elzehery, Rasha |
author_sort | Elsehely, Ibrahim |
collection | PubMed |
description | Previous studies showed that early age at menarche is associated with increased risk of metabolic syndrome. However, the definition of early menarche at these studies was based on background data in the communities at which these studies was carried on. The aim of this work is to determine a cutoff for age at menarche discriminating presence or absence of metabolic syndrome in overweight/obese premenopausal women. This study included 204 overweight/obese women. Metabolic syndrome was defined according to NCEP-ATP III (National Cholesterol Education Program Adult Treatment Panel III) criteria. Of a total 204 participants, 82 (40.2%) had metabolic syndrome. By using receiver operating characteristic analysis, age at menarche ≤12.25 year discriminated individuals with from those without metabolic syndrome. The area under the curve was 0.76 (95% confidence interval, 0.70 to 0.83). Sensitivity, specificity, negative predictive value, and positive predictive value were 82%, 70%, 85%, and 64%, respectively. Age at menarche ≤12.25 years predicts the presence of metabolic syndrome in overweight/obese women. |
format | Online Article Text |
id | pubmed-5409008 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Korean Diabetes Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-54090082017-05-01 A Cutoff for Age at Menarche Predicting Metabolic Syndrome in Egyptian Overweight/Obese Premenopausal Women Elsehely, Ibrahim Abdel Hafez, Hala Ghonem, Mohammed Fathi, Ali Elzehery, Rasha Diabetes Metab J Brief Report Previous studies showed that early age at menarche is associated with increased risk of metabolic syndrome. However, the definition of early menarche at these studies was based on background data in the communities at which these studies was carried on. The aim of this work is to determine a cutoff for age at menarche discriminating presence or absence of metabolic syndrome in overweight/obese premenopausal women. This study included 204 overweight/obese women. Metabolic syndrome was defined according to NCEP-ATP III (National Cholesterol Education Program Adult Treatment Panel III) criteria. Of a total 204 participants, 82 (40.2%) had metabolic syndrome. By using receiver operating characteristic analysis, age at menarche ≤12.25 year discriminated individuals with from those without metabolic syndrome. The area under the curve was 0.76 (95% confidence interval, 0.70 to 0.83). Sensitivity, specificity, negative predictive value, and positive predictive value were 82%, 70%, 85%, and 64%, respectively. Age at menarche ≤12.25 years predicts the presence of metabolic syndrome in overweight/obese women. Korean Diabetes Association 2017-04 2016-11-30 /pmc/articles/PMC5409008/ /pubmed/28447441 http://dx.doi.org/10.4093/dmj.2017.41.2.146 Text en Copyright © 2017 Korean Diabetes Association http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Brief Report Elsehely, Ibrahim Abdel Hafez, Hala Ghonem, Mohammed Fathi, Ali Elzehery, Rasha A Cutoff for Age at Menarche Predicting Metabolic Syndrome in Egyptian Overweight/Obese Premenopausal Women |
title | A Cutoff for Age at Menarche Predicting Metabolic Syndrome in Egyptian Overweight/Obese Premenopausal Women |
title_full | A Cutoff for Age at Menarche Predicting Metabolic Syndrome in Egyptian Overweight/Obese Premenopausal Women |
title_fullStr | A Cutoff for Age at Menarche Predicting Metabolic Syndrome in Egyptian Overweight/Obese Premenopausal Women |
title_full_unstemmed | A Cutoff for Age at Menarche Predicting Metabolic Syndrome in Egyptian Overweight/Obese Premenopausal Women |
title_short | A Cutoff for Age at Menarche Predicting Metabolic Syndrome in Egyptian Overweight/Obese Premenopausal Women |
title_sort | cutoff for age at menarche predicting metabolic syndrome in egyptian overweight/obese premenopausal women |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409008/ https://www.ncbi.nlm.nih.gov/pubmed/28447441 http://dx.doi.org/10.4093/dmj.2017.41.2.146 |
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