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Social defeat stress causes depression-like behavior with metabolite changes in the prefrontal cortex of rats
Major depressive disorder is a serious mental disorder with high morbidity and mortality. The role of social stress in the development of depression remains unclear. Here, we used the social defeat stress paradigm to induce depression-like behavior in rats, then evaluated the behavior of the rats an...
Autores principales: | Liu, Yi-Yun, Zhou, Xin-Yu, Yang, Li-Ning, Wang, Hai-Yang, Zhang, Yu-Qing, Pu, Jun-Cai, Liu, Lan-Xiang, Gui, Si-Wen, Zeng, Li, Chen, Jian-Jun, Zhou, Chan-Juan, Xie, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409051/ https://www.ncbi.nlm.nih.gov/pubmed/28453574 http://dx.doi.org/10.1371/journal.pone.0176725 |
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