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Properties of human disease genes and the role of genes linked to Mendelian disorders in complex disease aetiology
Do genes presenting variation that has been linked to human disease have different biological properties than genes that have never been related to disease? What is the relationship between disease and fitness? Are the evolutionary pressures that affect genes linked to Mendelian diseases the same to...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409085/ https://www.ncbi.nlm.nih.gov/pubmed/28053046 http://dx.doi.org/10.1093/hmg/ddw405 |