Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson’s disease

While induced pluripotent stem cell (iPSC) technologies enable the study of inaccessible patient cell types, cellular heterogeneity can confound the comparison of gene expression profiles between iPSC-derived cell lines. Here, we purified iPSC-derived human dopaminergic neurons (DaNs) using the intr...

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Detalles Bibliográficos
Autores principales: Sandor, Cynthia, Robertson, Paul, Lang, Charmaine, Heger, Andreas, Booth, Heather, Vowles, Jane, Witty, Lorna, Bowden, Rory, Hu, Michele, Cowley, Sally A., Wade-Martins, Richard, Webber, Caleb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409122/
https://www.ncbi.nlm.nih.gov/pubmed/28096185
http://dx.doi.org/10.1093/hmg/ddw412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409122/
https://www.ncbi.nlm.nih.gov/pubmed/28096185
http://dx.doi.org/10.1093/hmg/ddw412

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