Polycomb repressive complex 1 provides a molecular explanation for repeat copy number dependency in FSHD muscular dystrophy

Repression of repetitive elements is crucial to preserve genome integrity and has been traditionally ascribed to constitutive heterochromatin pathways. FacioScapuloHumeral Muscular Dystrophy (FSHD), one of the most common myopathies, is characterized by a complex interplay of genetic and epigenetic...

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Detalles Bibliográficos
Autores principales: Casa, Valentina, Runfola, Valeria, Micheloni, Stefano, Aziz, Arif, Dilworth, F. Jeffrey, Gabellini, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409123/
https://www.ncbi.nlm.nih.gov/pubmed/28040729
http://dx.doi.org/10.1093/hmg/ddw426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409123/
https://www.ncbi.nlm.nih.gov/pubmed/28040729
http://dx.doi.org/10.1093/hmg/ddw426

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