Loss of Arf4 causes severe degeneration of the exocrine pancreas but not cystic kidney disease or retinal degeneration

Arf4 is proposed to be a critical regulator of membrane protein trafficking in early secretory pathway. More recently, Arf4 was also implicated in regulating ciliary trafficking, however, this has not been comprehensively tested in vivo. To directly address Arf4’s role in ciliary transport, we delet...

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Detalles Bibliográficos
Autores principales: Pearring, Jillian N., San Agustin, Jovenal T., Lobanova, Ekaterina S., Gabriel, Christopher J., Lieu, Eric C., Monis, William J., Stuck, Michael W., Strittmatter, Lara, Jaber, Samer M., Arshavsky, Vadim Y., Pazour, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409180/
https://www.ncbi.nlm.nih.gov/pubmed/28410364
http://dx.doi.org/10.1371/journal.pgen.1006740

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