MGMT-Methylated Alleles Are Distributed Heterogeneously Within Glioma Samples Irrespective of IDH Status and Chromosome 10q Deletion

Several molecular markers drive diagnostic classification, prognostic stratification, and/or prediction of response to therapy in patients with gliomas. Among them, IDH gene mutations are valuable markers for defining subtypes and are strongly associated with epigenetic silencing of the methylguanin...

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Detalles Bibliográficos
Autores principales: Fontana, Laura, Tabano, Silvia, Bonaparte, Eleonora, Marfia, Giovanni, Pesenti, Chiara, Falcone, Rossella, Augello, Claudia, Carlessi, Nicole, Silipigni, Rosamaria, Guerneri, Silvana, Campanella, Rolando, Caroli, Manuela, Maria Sirchia, Silvia, Bosari, Silvano, Miozzo, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409217/
https://www.ncbi.nlm.nih.gov/pubmed/27346749
http://dx.doi.org/10.1093/jnen/nlw052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409217/
https://www.ncbi.nlm.nih.gov/pubmed/27346749
http://dx.doi.org/10.1093/jnen/nlw052

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