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Vitamin B12 ameliorates the phenotype of a mouse model of DiGeorge syndrome
Pathological conditions caused by reduced dosage of a gene, such as gene haploinsufficiency, can potentially be reverted by enhancing the expression of the functional allele. In practice, low specificity of therapeutic agents, or their toxicity reduces their clinical applicability. Here, we have use...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409220/ https://www.ncbi.nlm.nih.gov/pubmed/28173146 http://dx.doi.org/10.1093/hmg/ddw267 |