Vitamin B12 ameliorates the phenotype of a mouse model of DiGeorge syndrome

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Pathological conditions caused by reduced dosage of a gene, such as gene haploinsufficiency, can potentially be reverted by enhancing the expression of the functional allele. In practice, low specificity of therapeutic agents, or their toxicity reduces their clinical applicability. Here, we have use...

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Detalles Bibliográficos
Autores principales: Lania, Gabriella, Bresciani, Alberto, Bisbocci, Monica, Francone, Alessandra, Colonna, Vincenza, Altamura, Sergio, Baldini, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409220/
https://www.ncbi.nlm.nih.gov/pubmed/28173146
http://dx.doi.org/10.1093/hmg/ddw267
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