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Detection of Copy Number Alterations Using Single Cell Sequencing

Detection of genomic changes at single cell resolution is important for characterizing genetic heterogeneity and evolution in normal tissues, cancers, and microbial populations. Traditional methods for assessing genetic heterogeneity have been limited by low resolution, low sensitivity, and/or low s...

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Detalles Bibliográficos
Autores principales: Knouse, Kristin A., Wu, Jie, Hendricks, Austin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409325/
https://www.ncbi.nlm.nih.gov/pubmed/28287554
http://dx.doi.org/10.3791/55143