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Folding of a single domain protein entering the endoplasmic reticulum precedes disulfide formation

The relationship between protein synthesis, folding, and disulfide formation within the endoplasmic reticulum (ER) is poorly understood. Previous studies have suggested that pre-existing disulfide links are absolutely required to allow protein folding and, conversely, that protein folding occurs pri...

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Detalles Bibliográficos
Autores principales:	Robinson, Philip J., Pringle, Marie Anne, Woolhead, Cheryl A., Bulleid, Neil J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2017
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409466/ https://www.ncbi.nlm.nih.gov/pubmed/28298446 http://dx.doi.org/10.1074/jbc.M117.780742

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