Regulatory T cells promote myelin regeneration in the Central Nervous System

Regeneration of central nervous system (CNS) myelin involves differentiation of oligodendrocytes from oligodendrocyte progenitor cells (OPC). In multiple sclerosis (MS), remyelination can fail despite abundant OPC, suggesting impairment of oligodendrocyte differentiation. T cells infiltrate the CNS...

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Detalles Bibliográficos
Autores principales: Dombrowski, Yvonne, O’Hagan, Thomas, Dittmer, Marie, Penalva, Rosana, Mayoral, Sonia R., Bankhead, Peter, Fleville, Samara, Eleftheriadis, George, Zhao, Chao, Naughton, Michelle, Hassan, Rachel, Moffat, Jill, Falconer, John, Boyd, Amanda, Hamilton, Peter, Allen, Ingrid V., Kissenpfennig, Adrien, Moynagh, Paul N., Evergren, Emma, Perbal, Bernard, Williams, Anna C., Ingram, Rebecca J., Chan, Jonah R., Franklin, Robin J.M., Fitzgerald, Denise C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409501/
https://www.ncbi.nlm.nih.gov/pubmed/28288125
http://dx.doi.org/10.1038/nn.4528

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