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Differential Gender Effects in the Relationship between Perceived Immune Functioning and Autistic Traits
Altered immune functioning has been demonstrated in individuals with autism spectrum disorder (ASD). The current study explores the relationship between perceived immune functioning and experiencing ASD traits in healthy young adults. N = 410 students from Utrecht University completed a survey on im...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409610/ https://www.ncbi.nlm.nih.gov/pubmed/28417950 http://dx.doi.org/10.3390/ijerph14040409 |
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author | Mackus, Marlou de Kruijff, Deborah Otten, Leila S. Kraneveld, Aletta D. Garssen, Johan Verster, Joris C. |
author_facet | Mackus, Marlou de Kruijff, Deborah Otten, Leila S. Kraneveld, Aletta D. Garssen, Johan Verster, Joris C. |
author_sort | Mackus, Marlou |
collection | PubMed |
description | Altered immune functioning has been demonstrated in individuals with autism spectrum disorder (ASD). The current study explores the relationship between perceived immune functioning and experiencing ASD traits in healthy young adults. N = 410 students from Utrecht University completed a survey on immune functioning and autistic traits. In addition to a 1-item perceived immune functioning rating, the Immune Function Questionnaire (IFQ) was completed to assess perceived immune functioning. The Dutch translation of the Autism-Spectrum Quotient (AQ) was completed to examine variation in autistic traits, including the domains “social insights and behavior”, “difficulties with change”, “communication”, “phantasy and imagination”, and “detail orientation”. The 1-item perceived immune functioning score did not significantly correlate with the total AQ score. However, a significant negative correlation was found between perceived immune functioning and the AQ subscale “difficulties with change” (r = −0.119, p = 0.019). In women, 1-item perceived immune functioning correlated significantly with the AQ subscales “difficulties with change” (r = −0.149, p = 0.029) and “communication” (r = −0.145, p = 0.032). In men, none of the AQ subscales significantly correlated with 1-item perceived immune functioning. In conclusion, a modest relationship between perceived immune functioning and several autistic traits was found. |
format | Online Article Text |
id | pubmed-5409610 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-54096102017-05-03 Differential Gender Effects in the Relationship between Perceived Immune Functioning and Autistic Traits Mackus, Marlou de Kruijff, Deborah Otten, Leila S. Kraneveld, Aletta D. Garssen, Johan Verster, Joris C. Int J Environ Res Public Health Article Altered immune functioning has been demonstrated in individuals with autism spectrum disorder (ASD). The current study explores the relationship between perceived immune functioning and experiencing ASD traits in healthy young adults. N = 410 students from Utrecht University completed a survey on immune functioning and autistic traits. In addition to a 1-item perceived immune functioning rating, the Immune Function Questionnaire (IFQ) was completed to assess perceived immune functioning. The Dutch translation of the Autism-Spectrum Quotient (AQ) was completed to examine variation in autistic traits, including the domains “social insights and behavior”, “difficulties with change”, “communication”, “phantasy and imagination”, and “detail orientation”. The 1-item perceived immune functioning score did not significantly correlate with the total AQ score. However, a significant negative correlation was found between perceived immune functioning and the AQ subscale “difficulties with change” (r = −0.119, p = 0.019). In women, 1-item perceived immune functioning correlated significantly with the AQ subscales “difficulties with change” (r = −0.149, p = 0.029) and “communication” (r = −0.145, p = 0.032). In men, none of the AQ subscales significantly correlated with 1-item perceived immune functioning. In conclusion, a modest relationship between perceived immune functioning and several autistic traits was found. MDPI 2017-04-12 2017-04 /pmc/articles/PMC5409610/ /pubmed/28417950 http://dx.doi.org/10.3390/ijerph14040409 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Mackus, Marlou de Kruijff, Deborah Otten, Leila S. Kraneveld, Aletta D. Garssen, Johan Verster, Joris C. Differential Gender Effects in the Relationship between Perceived Immune Functioning and Autistic Traits |
title | Differential Gender Effects in the Relationship between Perceived Immune Functioning and Autistic Traits |
title_full | Differential Gender Effects in the Relationship between Perceived Immune Functioning and Autistic Traits |
title_fullStr | Differential Gender Effects in the Relationship between Perceived Immune Functioning and Autistic Traits |
title_full_unstemmed | Differential Gender Effects in the Relationship between Perceived Immune Functioning and Autistic Traits |
title_short | Differential Gender Effects in the Relationship between Perceived Immune Functioning and Autistic Traits |
title_sort | differential gender effects in the relationship between perceived immune functioning and autistic traits |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409610/ https://www.ncbi.nlm.nih.gov/pubmed/28417950 http://dx.doi.org/10.3390/ijerph14040409 |
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