Cargando…

Evaluation of the Effects of Airborne Particulate Matter on Bone Marrow-Mesenchymal Stem Cells (BM-MSCs): Cellular, Molecular and Systems Biological Approaches

Particulate matter (PM) contains heavy metals that affect various cellular functions and gene expression associated with a range of acute and chronic diseases in humans. However, the specific effects they exert on the stem cells remain unclear. Here, we report the effects of PM collected from the ci...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abu-Elmagd, Muhammad, Alghamdi, Mansour A., Shamy, Magdy, Khoder, Mamdouh I., Costa, Max, Assidi, Mourad, Kadam, Roaa, Alsehli, Haneen, Gari, Mamdooh, Pushparaj, Peter Natesan, Kalamegam, Gauthaman, Al-Qahtani, Mohammed H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409640/ https://www.ncbi.nlm.nih.gov/pubmed/28425934 http://dx.doi.org/10.3390/ijerph14040440

Ejemplares similares

Pelleted Bone Marrow Derived Mesenchymal Stem Cells Are Better Protected from the Deleterious Effects of Arthroscopic Heat Shock
por: Kalamegam, Gauthaman, et al.
Publicado: (2016)

Identification of novel genetic variations affecting osteoarthritis patients
por: Gari, Mamdooh Abdullah, et al.
Publicado: (2016)

Unraveling the Catha edulis Extract Effects on the Cellular and Molecular Signaling in SKOV3 Cells
por: Abou-Elhamd, Alaa Sayed, et al.
Publicado: (2021)

The Third International Genomic Medicine Conference (3rd IGMC, 2015): overall activities and outcome highlights
por: Abu-Elmagd, Muhammad, et al.
Publicado: (2016)

Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis
por: Kalamegam, Gauthaman, et al.
Publicado: (2018)

Corrigendum: Human Wharton’s Jelly stem cell (hWJSC) extracts inhibit ovarian cancer cell lines OVCAR3 and SKOV3 in vitro by inducing cell cycle arrest and apoptosis
por: Kalamegam, Gauthaman, et al.
Publicado: (2023)

Thymoquinone (TQ) Inhibits Inflammation and Migration of THP-1 Macrophages: Mechanistic Insights into the Prevention of Atherosclerosis Using In-Vitro and In-Silico Analysis
por: Huwait, Etimad, et al.
Publicado: (2022)

Molecular docking of resveratrol with known protein structures as well as high-throughput meta-data analyses uncork the “French Paradox” and its potential “Druggable” targets in humans
por: Pushparaj, Peter Natesan, et al.
Publicado: (2014)

In vitro Evaluation of the Anti-inflammatory Effects of Thymoquinone in Osteoarthritis and in silico Analysis of Inter-Related Pathways in Age-Related Degenerative Diseases
por: Kalamegam, Gauthaman, et al.
Publicado: (2020)

Cytokines secreted by human Wharton's jelly stem cells inhibit the proliferation of ovarian cancer (OVCAR3) cells in vitro
por: Kalamegam, Gauthaman, et al.
Publicado: (2019)

Method of delivery of bone marrow stem cells to the articular joint influences their survival during arthroscopy
por: Al Nono, Reham, et al.
Publicado: (2014)

Editorial: Methods and application in integrative and regenerative pharmacology: 2021
por: Pushparaj, Peter Natesan, et al.
Publicado: (2022)

Integration of palliative care in the management of oral squamous cell carcinoma
por: Sridhar, Republica, et al.
Publicado: (2023)

Individualized medicine enabled by genomics in Saudi Arabia
por: Abu-Elmagd, Muhammad, et al.
Publicado: (2015)

Role of the antineoplastic drug bleomycin based on toxicogenomic-DNA damage inducing (TGx-DDI) genomic biomarkers data: A meta-analysis
por: Pushparaj, Peter Natesan, et al.
Publicado: (2023)

Exploration of potential molecular mechanisms and genotoxicity of anti-cancer drugs using next generation knowledge discovery methods
por: Pushparaj, Peter Natesan, et al.
Publicado: (2023)

Primary ovarian cancer cell inhibition by human Wharton's Jelly stem cells (hWJSCs): Mapping probable mechanisms and targets using systems oncology
por: Kalamegam, Gauthaman, et al.
Publicado: (2015)

Decoding the Role of Astrocytes in the Entorhinal Cortex in Alzheimer’s Disease Using High-Dimensional Single-Nucleus RNA Sequencing Data and Next-Generation Knowledge Discovery Methodologies: Focus on Drugs and Natural Product Remedies for Dementia
por: Pushparaj, Peter Natesan, et al.
Publicado: (2022)

Ajwa Date (Phoenix dactylifera L.) Extract Inhibits Human Breast Adenocarcinoma (MCF7) Cells In Vitro by Inducing Apoptosis and Cell Cycle Arrest
por: Khan, Fazal, et al.
Publicado: (2016)

Human Wharton’s Jelly Stem Cell Secretions Inhibit Human Leukemic Cell Line K562 in vitro by Inducing Cell Cycle Arrest and Apoptosis
por: Huwaikem, Muneerah A. H., et al.
Publicado: (2021)

Anti-cancer effects of Ajwa dates (Phoenix dactylifera L.) in diethylnitrosamine induced hepatocellular carcinoma in Wistar rats
por: Khan, Fazal, et al.
Publicado: (2017)

Expression pattern, prognostic value and potential microRNA silencing of FZD8 in breast cancer
por: Al-Zahrani, Maryam H., et al.
Publicado: (2023)

Evaluation of the effect of Nigella sativa extract on human hepatocellular adenocarcinoma cell line (HepG2) in vitro
por: Khan, Fazal, et al.
Publicado: (2014)

Incidence and potential causative factors associated with chronic benign neutropenia in the Kingdom of Saudi Arabia
por: Gari, Mamdooh, et al.
Publicado: (2015)

Role of Oxidative Stress and the Identification of Biomarkers Associated With Thyroid Dysfunction in Schizophrenics
por: Rasool, Mahmood, et al.
Publicado: (2021)

Risk Assessment and Implication of Human Exposure to Road Dust Heavy Metals in Jeddah, Saudi Arabia
por: Shabbaj, Ibrahim I., et al.
Publicado: (2017)

Antiatherogenic Effects of Quercetin in the THP-1 Macrophage Model In Vitro, With Insights Into Its Signaling Mechanisms Using In Silico Analysis
por: Huwait, Etimad A., et al.
Publicado: (2021)

Disease associated cellular machinery in anaphylaxis – And the de novo paradigm shift
por: Pushparaj, Peter Natesan, et al.
Publicado: (2015)

Association between sleeping hours and cardiometabolic risk factors for metabolic syndrome in a Saudi Arabian population
por: Brocato, Jason, et al.
Publicado: (2015)

Array comparative genomic hybridization based identification of key genetic alterations at 2p21-p16.3 (MSH2, MSH6, EPCAM), 3p23-p14.2 (MLH1), 7p22.1 (PMS2) and 1p34.1-p33 (MUTYH) regions in hereditary non polyposis colorectal cancer (Lynch syndrome) in the Kingdom of Saudi Arabia
por: Rasool, Mahmood, et al.
Publicado: (2020)

Hyperleukocytic Acute Leukemia Circulating Exosomes Regulate HSCs and BM-MSCs
por: Yang, Yanmei, et al.
Publicado: (2021)

AD-MSCs and BM-MSCs Ameliorating Effects on The Metabolic and Hepato-renal Abnormalities in Type 1 Diabetic Rats
por: El-Sawah, Shady G., et al.
Publicado: (2022)

Copy number variations in Saudi family with intellectual disability and epilepsy
por: Naseer, Muhammad I., et al.
Publicado: (2016)

Evaluation of in vitro chondrocytic differentiation: A stem cell research initiative at the King Abdulaziz University, Kingdom of Saudi Arabia
por: Al-Yamani, Aisha, et al.
Publicado: (2018)

BM-MSCs differentiated to chondrocytes for treatment of full-thickness cartilage defect of the knee
por: Mardones, Rodrigo, et al.
Publicado: (2020)

Retracted: Hyperleukocytic Acute Leukemia Circulating Exosomes Regulate HSCs and BM-MSCs
por: Healthcare Engineering, Journal of
Publicado: (2022)

Deciphering the Association of Cytokines, Chemokines, and Growth Factors in Chondrogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells Using an ex vivo Osteochondral Culture System
por: Jafri, Mohammad Alam, et al.
Publicado: (2020)

Editorial: Advances in genomic and genetic tools, and their applications for understanding embryonic development and human diseases
por: Abu-Elmagd, Muhammad, et al.
Publicado: (2022)

Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015): Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015
por: Shay, Jerry W., et al.
Publicado: (2016)

Pretreatment with G-CSF Could Enhance the Antifibrotic Effect of BM-MSCs on Pulmonary Fibrosis
por: Zhao, Feiyan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_l2ng33am5j6753e1i964mpehpf