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Very Low Volume Sprint Interval Exercise Suppresses Subjective Appetite, Lowers Acylated Ghrelin, and Elevates GLP-1 in Overweight Individuals: A Pilot Study

High-intensity exercise has been shown to elicit a transient suppression of appetite and create a more anorexigenic profile of appetite-associated hormones. It is yet to be fully elucidated whether such a response is observed following very low-volume, intermittent exercise at supramaximal intensity...

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Autores principales: Holliday, Adrian, Blannin, Andrew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409701/
https://www.ncbi.nlm.nih.gov/pubmed/28379172
http://dx.doi.org/10.3390/nu9040362
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author Holliday, Adrian
Blannin, Andrew K.
author_facet Holliday, Adrian
Blannin, Andrew K.
author_sort Holliday, Adrian
collection PubMed
description High-intensity exercise has been shown to elicit a transient suppression of appetite and create a more anorexigenic profile of appetite-associated hormones. It is yet to be fully elucidated whether such a response is observed following very low-volume, intermittent exercise at supramaximal intensity in those who are overweight. Eight overweight individuals (BMI 27.7 ± 1.7 kg·m(2)) completed resting (REST) and exercise (EX) trials in a counterbalanced order. EX consisted of 4 × 30 s “flat-out” cycling on an ergometer (adapted Wingate test). Two hours post-exercise (or REST), participants were presented with an ad libitum meal. Subjective appetite measures and blood samples were obtained throughout. Subjective appetite, measured using VAS, was significantly lower immediately after exercise compared with REST (38.0 ± 28.5 mm vs. 75.1 ± 26.2 mm, p = 0.018, d = 1.09). This difference remained significant 30 min post-exercise. Acylated ghrelin concentration was suppressed in EX compared with REST immediately post-exercise (113.4 ± 43.0 pg·mL(−1) vs. 189.2 ± 91.8 pg·mL(−1), p = 0.03, d = 1.07) and remained lower until the ad libitum test-meal. Area-under-the-curve for GLP-1 concentration was significantly greater for EX, versus REST. There was no difference in absolute ad libitum intake or relative energy intake. As little as 4 × 30 s of “flat-out” cycling was sufficient to elicit a transient suppression of appetite and an enduring suppression of plasma acylated ghrelin. Nonetheless, food intake 2-h post-exercise was unaffected.
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spelling pubmed-54097012017-05-03 Very Low Volume Sprint Interval Exercise Suppresses Subjective Appetite, Lowers Acylated Ghrelin, and Elevates GLP-1 in Overweight Individuals: A Pilot Study Holliday, Adrian Blannin, Andrew K. Nutrients Article High-intensity exercise has been shown to elicit a transient suppression of appetite and create a more anorexigenic profile of appetite-associated hormones. It is yet to be fully elucidated whether such a response is observed following very low-volume, intermittent exercise at supramaximal intensity in those who are overweight. Eight overweight individuals (BMI 27.7 ± 1.7 kg·m(2)) completed resting (REST) and exercise (EX) trials in a counterbalanced order. EX consisted of 4 × 30 s “flat-out” cycling on an ergometer (adapted Wingate test). Two hours post-exercise (or REST), participants were presented with an ad libitum meal. Subjective appetite measures and blood samples were obtained throughout. Subjective appetite, measured using VAS, was significantly lower immediately after exercise compared with REST (38.0 ± 28.5 mm vs. 75.1 ± 26.2 mm, p = 0.018, d = 1.09). This difference remained significant 30 min post-exercise. Acylated ghrelin concentration was suppressed in EX compared with REST immediately post-exercise (113.4 ± 43.0 pg·mL(−1) vs. 189.2 ± 91.8 pg·mL(−1), p = 0.03, d = 1.07) and remained lower until the ad libitum test-meal. Area-under-the-curve for GLP-1 concentration was significantly greater for EX, versus REST. There was no difference in absolute ad libitum intake or relative energy intake. As little as 4 × 30 s of “flat-out” cycling was sufficient to elicit a transient suppression of appetite and an enduring suppression of plasma acylated ghrelin. Nonetheless, food intake 2-h post-exercise was unaffected. MDPI 2017-04-05 /pmc/articles/PMC5409701/ /pubmed/28379172 http://dx.doi.org/10.3390/nu9040362 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Holliday, Adrian
Blannin, Andrew K.
Very Low Volume Sprint Interval Exercise Suppresses Subjective Appetite, Lowers Acylated Ghrelin, and Elevates GLP-1 in Overweight Individuals: A Pilot Study
title Very Low Volume Sprint Interval Exercise Suppresses Subjective Appetite, Lowers Acylated Ghrelin, and Elevates GLP-1 in Overweight Individuals: A Pilot Study
title_full Very Low Volume Sprint Interval Exercise Suppresses Subjective Appetite, Lowers Acylated Ghrelin, and Elevates GLP-1 in Overweight Individuals: A Pilot Study
title_fullStr Very Low Volume Sprint Interval Exercise Suppresses Subjective Appetite, Lowers Acylated Ghrelin, and Elevates GLP-1 in Overweight Individuals: A Pilot Study
title_full_unstemmed Very Low Volume Sprint Interval Exercise Suppresses Subjective Appetite, Lowers Acylated Ghrelin, and Elevates GLP-1 in Overweight Individuals: A Pilot Study
title_short Very Low Volume Sprint Interval Exercise Suppresses Subjective Appetite, Lowers Acylated Ghrelin, and Elevates GLP-1 in Overweight Individuals: A Pilot Study
title_sort very low volume sprint interval exercise suppresses subjective appetite, lowers acylated ghrelin, and elevates glp-1 in overweight individuals: a pilot study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409701/
https://www.ncbi.nlm.nih.gov/pubmed/28379172
http://dx.doi.org/10.3390/nu9040362
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