Atrophin controls developmental signaling pathways via interactions with Trithorax-like

Mutations in human Atrophin1, a transcriptional corepressor, cause dentatorubral-pallidoluysian atrophy, a neurodegenerative disease. Drosophila Atrophin (Atro) mutants display many phenotypes, including neurodegeneration, segmentation, patterning and planar polarity defects. Despite Atro’s critical...

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Detalles Bibliográficos
Autores principales: Yeung, Kelvin, Boija, Ann, Karlsson, Edvin, Holmqvist, Per-Henrik, Tsatskis, Yonit, Nisoli, Ilaria, Yap, Damian, Lorzadeh, Alireza, Moksa, Michelle, Hirst, Martin, Aparicio, Samuel, Fanto, Manolis, Stenberg, Per, Mannervik, Mattias, McNeill, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409829/
https://www.ncbi.nlm.nih.gov/pubmed/28327288
http://dx.doi.org/10.7554/eLife.23084

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