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Two years post affordable medicines facility for malaria program: availability and prices of anti-malarial drugs in central Ghana

BACKGROUND: The Affordable Medicines Facility for malaria (AMFm) Program was a subsidy aimed at artemisinin-based combination therapies (ACTs) in order to increase availability, affordability, and market share of ACTs in 8 malaria endemic countries in Africa. The WHO supervised the manufacture of th...

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Autores principales: Freeman, Alexander, Kwarteng, Anthony, Febir, Lawrence Gyabaa, Amenga-Etego, Seeba, Owusu-Agyei, Seth, Asante, Kwaku Poku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410094/
https://www.ncbi.nlm.nih.gov/pubmed/28465829
http://dx.doi.org/10.1186/s40545-017-0103-0
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author Freeman, Alexander
Kwarteng, Anthony
Febir, Lawrence Gyabaa
Amenga-Etego, Seeba
Owusu-Agyei, Seth
Asante, Kwaku Poku
author_facet Freeman, Alexander
Kwarteng, Anthony
Febir, Lawrence Gyabaa
Amenga-Etego, Seeba
Owusu-Agyei, Seth
Asante, Kwaku Poku
author_sort Freeman, Alexander
collection PubMed
description BACKGROUND: The Affordable Medicines Facility for malaria (AMFm) Program was a subsidy aimed at artemisinin-based combination therapies (ACTs) in order to increase availability, affordability, and market share of ACTs in 8 malaria endemic countries in Africa. The WHO supervised the manufacture of the subsidized products, named them Quality Assured ACTs (QAACT) and printed a Green Leaf Logo on all QAACT packages. Ghana began to receive the subsidized QAACTs in 2010. METHODS: A cross-sectional stock survey was conducted at 63 licensed chemical shops (LCS) and private pharmacies in two districts of the Brong-Ahafo region of Ghana to determine the availability and price of all anti-malarial treatments. Drug outlets were visited over a 3-weeks period in October and November of 2014, about 2 years after the end of AMFm program. RESULTS: At least one QAACT was available in 88.9% (95% CI 80.9% – 96.8%) of all drug outlets with no difference between urban and rural locations. Non-Assured ACTs (NAACT) were significantly more available in urban drug outlets [75.0% availability (95% CI 59.1% – 90.9%)] than in rural drug outlets [16.1% availability (95% CI 2.4% – 29.9%)]. The top selling product was Artemether Lumefantrine with the Green Leaf Logo, a QAACT. There was a significant difference in the mean price of a QAACT [$1.04 USD (95% CI $0.98 – $1.11)], and the mean price of a NAACT in both the urban and rural areas [$2.46 USD (95% CI $2.11 – $2.81)]. There was no significant difference in the price of any product that was available in urban and rural settings CONCLUSION: About 2 years after the AMFm program, subsidized QAACTs in Ghana were widely available and more affordable than NAACTs in the Kintampo North District and Kintampo South Municipality of Ghana. The AMFm program appeared to have mostly succeeded in making QAACTs available and affordable.
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spelling pubmed-54100942017-05-02 Two years post affordable medicines facility for malaria program: availability and prices of anti-malarial drugs in central Ghana Freeman, Alexander Kwarteng, Anthony Febir, Lawrence Gyabaa Amenga-Etego, Seeba Owusu-Agyei, Seth Asante, Kwaku Poku J Pharm Policy Pract Research BACKGROUND: The Affordable Medicines Facility for malaria (AMFm) Program was a subsidy aimed at artemisinin-based combination therapies (ACTs) in order to increase availability, affordability, and market share of ACTs in 8 malaria endemic countries in Africa. The WHO supervised the manufacture of the subsidized products, named them Quality Assured ACTs (QAACT) and printed a Green Leaf Logo on all QAACT packages. Ghana began to receive the subsidized QAACTs in 2010. METHODS: A cross-sectional stock survey was conducted at 63 licensed chemical shops (LCS) and private pharmacies in two districts of the Brong-Ahafo region of Ghana to determine the availability and price of all anti-malarial treatments. Drug outlets were visited over a 3-weeks period in October and November of 2014, about 2 years after the end of AMFm program. RESULTS: At least one QAACT was available in 88.9% (95% CI 80.9% – 96.8%) of all drug outlets with no difference between urban and rural locations. Non-Assured ACTs (NAACT) were significantly more available in urban drug outlets [75.0% availability (95% CI 59.1% – 90.9%)] than in rural drug outlets [16.1% availability (95% CI 2.4% – 29.9%)]. The top selling product was Artemether Lumefantrine with the Green Leaf Logo, a QAACT. There was a significant difference in the mean price of a QAACT [$1.04 USD (95% CI $0.98 – $1.11)], and the mean price of a NAACT in both the urban and rural areas [$2.46 USD (95% CI $2.11 – $2.81)]. There was no significant difference in the price of any product that was available in urban and rural settings CONCLUSION: About 2 years after the AMFm program, subsidized QAACTs in Ghana were widely available and more affordable than NAACTs in the Kintampo North District and Kintampo South Municipality of Ghana. The AMFm program appeared to have mostly succeeded in making QAACTs available and affordable. BioMed Central 2017-04-28 /pmc/articles/PMC5410094/ /pubmed/28465829 http://dx.doi.org/10.1186/s40545-017-0103-0 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Freeman, Alexander
Kwarteng, Anthony
Febir, Lawrence Gyabaa
Amenga-Etego, Seeba
Owusu-Agyei, Seth
Asante, Kwaku Poku
Two years post affordable medicines facility for malaria program: availability and prices of anti-malarial drugs in central Ghana
title Two years post affordable medicines facility for malaria program: availability and prices of anti-malarial drugs in central Ghana
title_full Two years post affordable medicines facility for malaria program: availability and prices of anti-malarial drugs in central Ghana
title_fullStr Two years post affordable medicines facility for malaria program: availability and prices of anti-malarial drugs in central Ghana
title_full_unstemmed Two years post affordable medicines facility for malaria program: availability and prices of anti-malarial drugs in central Ghana
title_short Two years post affordable medicines facility for malaria program: availability and prices of anti-malarial drugs in central Ghana
title_sort two years post affordable medicines facility for malaria program: availability and prices of anti-malarial drugs in central ghana
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410094/
https://www.ncbi.nlm.nih.gov/pubmed/28465829
http://dx.doi.org/10.1186/s40545-017-0103-0
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