Development of Flow Cytometry-Fluorescent In Situ Hybridization (Flow-FISH) Method for Detection of PML/RARa Chromosomal Translocation in Acute Promyelocytic Leukemia Cell Line

BACKGROUND: Acute Promyelocytic Leukemia (APL) is a subclass of acute myeloid leukemia. The chromosomal aberration in 95% of APL cases is t(15; 17) (q22; q21), which prevents cell differentiation. Characterization of the underlying molecular lesion is valuable in determining optimal treatment strate...

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Detalles Bibliográficos
Autores principales: Zahedipour, Fatemeh, Ranjbaran, Reza, Behzad Behbahani, Abbas, Afshari, Khalil Tavakol, Okhovat, Mohammad Ali, Tamadon, Gholamhossein, Sharifzadeh, Sedigheh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410127/
https://www.ncbi.nlm.nih.gov/pubmed/28496950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410127/
https://www.ncbi.nlm.nih.gov/pubmed/28496950

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