Multi-gene panel testing for hereditary cancer predisposition in unsolved high-risk breast and ovarian cancer patients

PURPOSE: Many women with an elevated risk of hereditary breast and ovarian cancer have previously tested negative for pathogenic mutations in BRCA1 and BRCA2. Among them, a subset has hereditary susceptibility to cancer and requires further testing. We sought to identify specific groups who remain a...

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Detalles Bibliográficos
Autores principales: Crawford, Beth, Adams, Sophie B., Sittler, Taylor, van den Akker, Jeroen, Chan, Salina, Leitner, Ofri, Ryan, Lauren, Gil, Elad, van ’t Veer, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410210/
https://www.ncbi.nlm.nih.gov/pubmed/28281021
http://dx.doi.org/10.1007/s10549-017-4181-0

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