Cargando…
Anthracyclines suppress pheochromocytoma cell characteristics, including metastasis, through inhibition of the hypoxia signaling pathway
Pheochromocytomas (PHEOs) and paragangliomas (PGLs) are rare, neuroendocrine tumors derived from adrenal or extra-adrenal chromaffin cells, respectively. Metastases are discovered in 3-36% of patients at the time of diagnosis. Currently, only suboptimal treatment options exist. Therefore, new therap...
Autores principales: | Pang, Ying, Yang, Chunzhang, Schovanek, Jan, Wang, Herui, Bullova, Petra, Caisova, Veronika, Gupta, Garima, Wolf, Katherine I., Semenza, Gregg L., Zhuang, Zhengping, Pacak, Karel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410225/ https://www.ncbi.nlm.nih.gov/pubmed/28423608 http://dx.doi.org/10.18632/oncotarget.16224 |
Ejemplares similares
-
Hypoxia potentiates the cytotoxic effect of piperlongumine in pheochromocytoma models
por: Bullova, Petra, et al.
Publicado: (2016) -
Vorinostat suppresses hypoxia signaling by modulating nuclear translocation of hypoxia inducible factor 1 alpha
por: Zhang, Chao, et al.
Publicado: (2017) -
Targeting NRF2-Governed Glutathione Synthesis for SDHB-Mutated Pheochromocytoma and Paraganglioma
por: Liu, Yang, et al.
Publicado: (2020) -
A novel splicing site IRP1 somatic mutation in a patient with pheochromocytoma and JAK2(V617F) positive polycythemia vera: a case report
por: Pang, Ying, et al.
Publicado: (2018) -
Pheochromocytomas and Paragangliomas: From Genetic Diversity to Targeted Therapies
por: Pang, Ying, et al.
Publicado: (2019)