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Overlooked FANCD2 variant encodes a promising, portent tumor suppressor, and alternative polyadenylation contributes to its expression
Fanconi Anemia (FA) complementation group D2 protein (FANCD2) is the center of the FA tumor suppressor pathway, which has become an important field of investigation in human aging and cancer. Here we report an overlooked central player in the FA pathway, FANCD2 variant 2 (FANCD2-V2), which appears t...
Autores principales: | Han, Bing, Shen, Yihang, Zhang, Piyan, Jayabal, Panneerselvam, Che, Raymond, Zhang, Jun, Yu, Herbert, Fei, Peiwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410239/ https://www.ncbi.nlm.nih.gov/pubmed/28157704 http://dx.doi.org/10.18632/oncotarget.14989 |
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