Cargando…
Inhibiting DNA-PKcs in a non-homologous end-joining pathway in response to DNA double-strand breaks
DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is a distinct factor in the non-homologous end-joining (NHEJ) pathway involved in DNA double-strand break (DSB) repair. We examined the crosstalk between key proteins in the DSB NHEJ repair pathway and cell cycle regulation and found that mou...
Autores principales: | Dong, Jun, Zhang, Tian, Ren, Yufeng, Wang, Zhenyu, Ling, Clifton C., He, Fuqiu, Li, Gloria C., Wang, Chengtao, Wen, Bixiu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410253/ https://www.ncbi.nlm.nih.gov/pubmed/28186989 http://dx.doi.org/10.18632/oncotarget.15153 |
Ejemplares similares
-
Inactivation of DNA-PK by knockdown DNA-PKcs or NU7441 impairs non-homologous end-joining of radiation-induced double strand break repair
por: Dong, Jun, et al.
Publicado: (2018) -
MicroRNA-145 Impairs Classical Non-Homologous End-Joining in Response to Ionizing Radiation-Induced DNA Double-Strand Breaks via Targeting DNA-PKcs
por: Sudhanva, Muddenahalli Srinivasa, et al.
Publicado: (2022) -
One end to rule them all: Non-homologous end-joining and homologous recombination at DNA double-strand breaks
por: Ensminger, Michael, et al.
Publicado: (2020) -
Processing of DNA double strand breaks by alternative non-homologous end-joining in hyperacetylated chromatin
por: Manova, Vasilissa, et al.
Publicado: (2012) -
DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining
por: Head, PamelaSara E, et al.
Publicado: (2023)