Efficacy of continuous EGFR-inhibition and role of Hedgehog in EGFR acquired resistance in human lung cancer cells with activating mutation of EGFR

PURPOSE: The aim of this work was to investigate the efficacy of sequential treatment with first-, second- and third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors and the mechanisms of acquired resistance occurring during the sequential use of these inhibitors. EXPERI...

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Detalles Bibliográficos
Autores principales: Della Corte, Carminia Maria, Malapelle, Umberto, Vigliar, Elena, Pepe, Francesco, Troncone, Giancarlo, Ciaramella, Vincenza, Troiani, Teresa, Martinelli, Erika, Belli, Valentina, Ciardiello, Fortunato, Morgillo, Floriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410282/
https://www.ncbi.nlm.nih.gov/pubmed/28416737
http://dx.doi.org/10.18632/oncotarget.15479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410282/
https://www.ncbi.nlm.nih.gov/pubmed/28416737
http://dx.doi.org/10.18632/oncotarget.15479

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