Cargando…

Resistance of leukemia cells to cytarabine chemotherapy is mediated by bone marrow stroma, involves cell-surface equilibrative nucleoside transporter-1 removal and correlates with patient outcome

The interaction between acute myeloid leukemia cells (AML) with the bone marrow stroma cells (BMSCs) determines a protective environment that favors tumor development and resistance to conventional chemotherapy. We showed that BMSCs secrete soluble factors that protect AML cells from Ara-C induced c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Macanas-Pirard, Patricia, Broekhuizen, Richard, González, Alfonso, Oyanadel, Claudia, Ernst, Daniel, García, Patricia, Montecinos, Viviana P., Court, Felipe, Ocqueteau, Mauricio, Ramirez, Pablo, Nervi, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410286/ https://www.ncbi.nlm.nih.gov/pubmed/28160570 http://dx.doi.org/10.18632/oncotarget.14981

Ejemplares similares

Bone Marrow Stromal Cells Modulate Mouse ENT1 Activity and Protect Leukemia Cells from Cytarabine Induced Apoptosis
por: Macanas-Pirard, Patricia, et al.
Publicado: (2012)

The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia
por: Hubeek, I, et al.
Publicado: (2005)

The CCL2/CCR2 Axis Affects Transmigration and Proliferation but Not Resistance to Chemotherapy of Acute Myeloid Leukemia Cells
por: Macanas-Pirard, Patricia, et al.
Publicado: (2017)

Role of equilibrative nucleoside transporter 1 (ENT1) in the disposition of cytarabine in mice
por: Anderson, Jason T., et al.
Publicado: (2019)

FLT3 is implicated in cytarabine transport by human equilibrative nucleoside transporter 1 in pediatric acute leukemia
por: Català, Albert, et al.
Publicado: (2016)

Modulation of the equilibrative nucleoside transporter by inhibitors of DNA synthesis.
por: Pressacco, J., et al.
Publicado: (1995)

Functional characterization of human equilibrative nucleoside transporter 1
por: Huang, Weiyun, et al.
Publicado: (2016)

Equilibrative Nucleoside Transporter 2: Properties and Physiological Roles
por: Naes, Safaa M., et al.
Publicado: (2020)

Targeting the equilibrative nucleoside transporter ENT1 in Huntington disease
por: Guitart, Xavier, et al.
Publicado: (2017)

Testicular disposition of clofarabine in rats is dependent on equilibrative nucleoside transporters
por: Miller, Siennah R., et al.
Publicado: (2021)

Adenosine Suppresses Cholangiocarcinoma Cell Growth and Invasion in Equilibrative Nucleoside Transporters-Dependent Pathway
por: Lertsuwan, Kornkamon, et al.
Publicado: (2020)

HIF-1–dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia
por: Eltzschig, Holger K., et al.
Publicado: (2005)

The Role of Flexible Loops in Folding, Trafficking and Activity of Equilibrative Nucleoside Transporters
por: Aseervatham, Jaya, et al.
Publicado: (2015)

Equilibrative Nucleoside Transporters Mediate the Import of Nicotinamide Riboside and Nicotinic Acid Riboside into Human Cells
por: Kropotov, Andrey, et al.
Publicado: (2021)

Metformin protects from oxaliplatin induced peripheral neuropathy in rats
por: Martinez, N.W., et al.
Publicado: (2020)

Identification of Structural and Molecular Features Involved in the Transport of 3′-Deoxy-Nucleoside Analogs by Human Equilibrative Nucleoside Transporter 3
por: Rahman, MD Fazlur, et al.
Publicado: (2018)

Export of RNA-derived modified nucleosides by equilibrative nucleoside transporters defines the magnitude of autophagy response and Zika virus replication
por: Shi, Sheng-Lan, et al.
Publicado: (2021)

Human equilibrative nucleoside transporter 1 gene expression is associated with gemcitabine efficacy in advanced leiomyosarcoma and angiosarcoma
por: Vincenzi, Bruno, et al.
Publicado: (2017)

Functional Characterization of the Saccharomyces cerevisiae Equilibrative Nucleoside Transporter 1 (ScENT1)
por: Boswell-Casteel, Rebba C., et al.
Publicado: (2018)

Sustained adenosine exposure causes endothelial mitochondrial dysfunction via equilibrative nucleoside transporters
por: Ko, Junsuk, et al.
Publicado: (2020)

Novel variants provide differential stabilisation of human equilibrative nucleoside transporter 1 states
por: Boakes, Jessica C., et al.
Publicado: (2022)

Structural basis for polymerase η–promoted resistance to the anticancer nucleoside analog cytarabine
por: Rechkoblit, Olga, et al.
Publicado: (2018)

Equilibrative nucleoside transporter 1 (ENT1) is critical for pollen germination and vegetative growth in Arabidopsis
por: Bernard, Carsten, et al.
Publicado: (2011)

Human equilibrative nucleoside transporter 1 and carcinoma of the ampulla of Vater: expression differences in tumour histotypes
por: Perrone, G., et al.
Publicado: (2010)

Changes in aortic reactivity associated with the loss of equilibrative nucleoside transporter 1 (ENT1) in mice
por: Best, K. Arielle, et al.
Publicado: (2018)

Equilibrative Nucleoside Transporters-1 Inhibitors Act as Anti-epileptic Agents by Inhibiting Glutamatergic Transmission
por: Ho, Shih-Yin, et al.
Publicado: (2020)

Equilibrative nucleoside transporter 1 inhibition rescues energy dysfunction and pathology in a model of tauopathy
por: Chang, Ching-Pang, et al.
Publicado: (2021)

Differential Inhibition of Equilibrative Nucleoside Transporter 1 (ENT1) Activity by Tyrosine Kinase Inhibitors
por: Jouan, Elodie, et al.
Publicado: (2021)

Human Equilibrative Nucleoside Transporter-1 Knockdown Tunes Cellular Mechanics through Epithelial-Mesenchymal Transition in Pancreatic Cancer Cells
por: Lee, Yeonju, et al.
Publicado: (2014)

Targeting the Plasmodium vivax equilibrative nucleoside transporter 1 (PvENT1) for antimalarial drug development
por: Deniskin, Roman, et al.
Publicado: (2015)

N-linked glycosylation of N48 is required for equilibrative nucleoside transporter 1 (ENT1) function
por: Bicket, Alex, et al.
Publicado: (2016)

Structural insights into mutagenicity of anticancer nucleoside analog cytarabine during replication by DNA polymerase η
por: Rechkoblit, Olga, et al.
Publicado: (2019)

Nucleoside transporter-guided cytarabine-conjugated liposomes for intracellular methotrexate delivery and cooperative choriocarcinoma therapy
por: Fei, Weidong, et al.
Publicado: (2021)

Type 1 equilibrative nucleoside transporter regulates astrocyte-specific glial fibrillary acidic protein expression in the striatum
por: Hinton, David J, et al.
Publicado: (2014)

Human Equilibrative Nucleoside Transporter 1 (hENT1) in Pancreatic Adenocarcinoma: Towards Individualized Treatment Decisions
por: Spratlin, Jennifer L., et al.
Publicado: (2010)

Deficient Insulin-mediated Upregulation of the Equilibrative Nucleoside Transporter 2 Contributes to Chronically Increased Adenosine in Diabetic Glomerulopathy
por: Alarcón, Sebastián, et al.
Publicado: (2017)

Neuronal activity-induced, equilibrative nucleoside transporter-dependent, somatodendritic adenosine release revealed by a GRAB sensor
por: Wu, Zhaofa, et al.
Publicado: (2023)

Primary Xenografts of Human Prostate Tissue as a Model to Study Angiogenesis Induced by Reactive Stroma
por: Montecinos, Viviana P., et al.
Publicado: (2012)

Decreased Equilibrative Nucleoside Transporter 1 (ENT1) Activity Contributes to the High Extracellular Adenosine Levels in Mesenchymal Glioblastoma Stem-Like Cells
por: Alarcón, Sebastián, et al.
Publicado: (2020)

Human equilibrative nucleoside transporter 1 and Notch3 can predict gemcitabine effects in patients with unresectable pancreatic cancer
por: Eto, K, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_qirf3kfo2sq4kjlsvolaobsqr5