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Resistance of leukemia cells to cytarabine chemotherapy is mediated by bone marrow stroma, involves cell-surface equilibrative nucleoside transporter-1 removal and correlates with patient outcome

The interaction between acute myeloid leukemia cells (AML) with the bone marrow stroma cells (BMSCs) determines a protective environment that favors tumor development and resistance to conventional chemotherapy. We showed that BMSCs secrete soluble factors that protect AML cells from Ara-C induced c...

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Detalles Bibliográficos
Autores principales:	Macanas-Pirard, Patricia, Broekhuizen, Richard, González, Alfonso, Oyanadel, Claudia, Ernst, Daniel, García, Patricia, Montecinos, Viviana P., Court, Felipe, Ocqueteau, Mauricio, Ramirez, Pablo, Nervi, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410286/ https://www.ncbi.nlm.nih.gov/pubmed/28160570 http://dx.doi.org/10.18632/oncotarget.14981

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