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The TERT promoter mutation incidence is modified by germline TERT rs2736098 and rs2736100 polymorphisms in hepatocellular carcinoma
Telomerase activation via induction of the catalytic component telomerase reverse transcriptase (TERT) plays essential roles in malignant transformation. TERT promoter-activating mutations were recently identified as a novel mechanism to activate telomerase in hepatocellular carcinoma (HCC) and many...
Autores principales: | Yuan, Xiaotian, Cheng, Guanghui, Yu, Jingya, Zheng, Shunzhen, Sun, Chao, Sun, Qing, Li, Kailin, Lin, Zhaomin, Liu, Tiantian, Li, Ping, Xu, Yiteng, Kong, Feng, Bjorkholm, Magnus, Xu, Dawei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410290/ https://www.ncbi.nlm.nih.gov/pubmed/28416747 http://dx.doi.org/10.18632/oncotarget.15498 |
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