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The cyclin-like protein, SPY1, regulates the ERα and ERK1/2 pathways promoting tamoxifen resistance

The Ras/Raf/MEK/ERK pathway conveys growth factor and mitogen signalling to control the phosphorylation of a plethora of substrates regulating proliferation, survival, and migration. The Ras signalling pathway is frequently associated with poor prognosis and drug resistance in various cancers includ...

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Detalles Bibliográficos
Autores principales:	Ferraiuolo, Rosa-Maria, Tubman, Janice, Sinha, Indrajit, Hamm, Caroline, Porter, Lisa Ann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410308/ https://www.ncbi.nlm.nih.gov/pubmed/28423577 http://dx.doi.org/10.18632/oncotarget.15578

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