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Shp2 confers cisplatin resistance in small cell lung cancer via an AKT-mediated increase in CA916798

The tyrosine phosphatase Shp2 is associated with tumorigenesis in small cell lung cancer (SCLC). However, the relationship between Shp2 and resistance to chemotherapy remains unclear. Here, we show that Shp2 plays an important role in inducing resistance to cisplatin-based chemotherapy via the SHP2-...

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Detalles Bibliográficos
Autores principales:	Yang, Xuemei, Tang, Chunlan, Luo, Hu, Wang, Haijing, Zhou, Xiangdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410335/ https://www.ncbi.nlm.nih.gov/pubmed/28423588 http://dx.doi.org/10.18632/oncotarget.15641

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