Cargando…

Adipose-derived mesenchymal stem cells promote osteosarcoma proliferation and metastasis by activating the STAT3 pathway

Osteosarcoma is the most common primary bone malignancy in children and young adults, but the role of adipose-derived mesenchymal stem cells (ADSCs) in the rapid progression of osteosarcoma is still unclear. Here, we found that ADSCs promoted tumour growth and invasion by increasing matrix metallopr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yan, Chu, Yijing, Yue, Bin, Ma, Xuexiao, Zhang, Guoqing, Xiang, Hongfei, Liu, Yong, Wang, Tianrui, Wu, Xiaolin, Chen, Bohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410345/ https://www.ncbi.nlm.nih.gov/pubmed/28423603 http://dx.doi.org/10.18632/oncotarget.15866

Ejemplares similares

Exosomes Secreted by Adipose-Derived Mesenchymal Stem Cells Foster Metastasis and Osteosarcoma Proliferation by Increasing COLGALT2 Expression
por: Wang, Yan, et al.
Publicado: (2020)

Epidural adipose tissue-derived mesenchymal stem cell activation induced by lung cancer cells promotes malignancy and EMT of lung cancer
por: Wang, Yan, et al.
Publicado: (2019)

Survivin is expressed in degenerated nucleus pulposus cells and is involved in proliferation and the prevention of apoptosis in vitro
por: LIN, YAZHOU, et al.
Publicado: (2016)

Upregulation of microRNA-25-3p inhibits proliferation, migration and invasion of osteosarcoma cells in vitro by directly targeting SOX4
por: Wu, Xiaolin, et al.
Publicado: (2022)

Construction and assessment of bio-engineered intervertebral discs
por: Xiang, Hongfei, et al.
Publicado: (2017)

Effect of lentivirus-mediated survivin transfection on the morphology and apoptosis of nucleus pulposus cells derived from degenerative human disc in vitro
por: MA, XUEXIAO, et al.
Publicado: (2015)

ADAMTS7 degrades Comp to fuel BMP2‐dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas
por: Wang, Chao, et al.
Publicado: (2020)

Differential proteomic analysis of fetal and geriatric lumbar nucleus pulposus: immunoinflammation and age-related intervertebral disc degeneration
por: Qiu, Chensheng, et al.
Publicado: (2020)

Effect of Survivin gene therapy via lentivirus vector on the course of intervertebral disc degeneration in an in vivo rabbit model
por: Yue, Bin, et al.
Publicado: (2016)

MNAT1 promotes proliferation and the chemo-resistance of osteosarcoma cell to cisplatin through regulating PI3K/Akt/mTOR pathway
por: Qiu, Chensheng, et al.
Publicado: (2020)

MicroRNA-212 suppresses the proliferation and migration of osteosarcoma cells by targeting forkhead box protein A1
por: Liu, Jian, et al.
Publicado: (2021)

Bone marrow mesenchymal stem cells promote osteosarcoma cell proliferation and invasion
por: Yu, Fu-Xiang, et al.
Publicado: (2015)

Histologic Observation and Significance of Sympathetic Nerve Fiber Distribution on Human Cervical Ligamentum Flavum
por: Wu, Xiaolin, et al.
Publicado: (2020)

Adipose-Derived Mesenchymal Stem Cells Enhance Ovarian Cancer Growth and Metastasis by Increasing Thymosin Beta 4X-Linked Expression
por: Chu, Yijing, et al.
Publicado: (2019)

The roles of metastasis-related proteins in the development of giant cell tumor of bone, osteosarcoma and Ewing’s sarcoma
por: Dou, Bo, et al.
Publicado: (2021)

Naringin targets Zeb1 to suppress osteosarcoma cell proliferation and metastasis
por: Ming, He, et al.
Publicado: (2018)

CEACAM6 is associated with osteosarcoma metastasis and facilitates epithelial–mesenchymal transition in osteosarcoma cells
por: Wang, Zeyu, et al.
Publicado: (2018)

miRNA-331-3p Affects the Proliferation, Metastasis, and Invasion of Osteosarcoma through SOCS1/JAK2/STAT3
por: Zu, Dan, et al.
Publicado: (2022)

Serglycin promotes proliferation, migration, and invasion via the JAK/STAT signaling pathway in osteosarcoma
por: Lv, Bin, et al.
Publicado: (2021)

ARHGEF3 Associated with Invasion, Metastasis, and Proliferation in Human Osteosarcoma
por: Gong, Jie, et al.
Publicado: (2021)

Mesenchymal stem cells promote osteosarcoma cell survival and drug resistance through activation of STAT3
por: Tu, Bing, et al.
Publicado: (2016)

Ilex hainanensis Merr targets ITGAV to suppress the proliferation and metastasis of osteosarcoma cells
por: Pei, Yi, et al.
Publicado: (2019)

Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway
por: Chu, Yijing, et al.
Publicado: (2021)

Elevated lymphotoxin-α (TNFβ) is associated with intervertebral disc degeneration
por: Guo, Zhu, et al.
Publicado: (2021)

The lncRNA NEAT1 promotes the epithelial-mesenchymal transition and metastasis of osteosarcoma cells by sponging miR-483 to upregulate STAT3 expression
por: Chen, Yan, et al.
Publicado: (2021)

Inhibition of STAT3 blocks protein synthesis and tumor metastasis in osteosarcoma cells
por: Zuo, Dongqing, et al.
Publicado: (2018)

Exosomal MATN3 of Urine-Derived Stem Cells Ameliorates Intervertebral Disc Degeneration by Antisenescence Effects and Promotes NPC Proliferation and ECM Synthesis by Activating TGF-β
por: Guo, Zhu, et al.
Publicado: (2021)

Tanshinone I inhibits the growth and metastasis of osteosarcoma via suppressing JAK/STAT3 signalling pathway
por: Wang, Weiguo, et al.
Publicado: (2019)

BMI1 promotes osteosarcoma proliferation and metastasis by repressing the transcription of SIK1
por: Wang, Qiang, et al.
Publicado: (2022)

lncRNA-CASC15 promotes osteosarcoma proliferation and metastasis by regulating epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway
por: Wang, Hongqi, et al.
Publicado: (2021)

lncRNA-CASC15 promotes osteosarcoma proliferation and metastasis by regulating epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway
por: Wang, Hongqi, et al.
Publicado: (2022)

Interleukin-22 Promotes Osteosarcoma Cell Proliferation and Invasion via STAT3 Activation
por: Li, Panpan, et al.
Publicado: (2018)

FBXO2 modulates STAT3 signaling to regulate proliferation and tumorigenicity of osteosarcoma cells
por: Zhao, Xunming, et al.
Publicado: (2020)

Cervical Transdural Discectomy with Laminoplasty for the Treatment of Multi‐segment Cervical Spinal Stenosis Accompanied with Cervical Disc Herniation: Technical Note and Clinical Outcome
por: Zhang, Hao, et al.
Publicado: (2021)

Gynura procumbens ethanolic extract suppresses osteosarcoma cell proliferation and metastasis in vitro
por: WANG, HENG, et al.
Publicado: (2013)

Silencing of carboxypeptidase E inhibits cell proliferation, tumorigenicity, and metastasis of osteosarcoma cells
por: Fan, Shuli, et al.
Publicado: (2016)

Chloroquine suppresses proliferation and invasion and induces apoptosis of osteosarcoma cells associated with inhibition of phosphorylation of STAT3
por: Chen, Chenglong, et al.
Publicado: (2021)

Beauvericin suppresses the proliferation and pulmonary metastasis of osteosarcoma by selectively inhibiting TGFBR2 pathway
por: Ye, Geni, et al.
Publicado: (2023)

Osteosarcoma and Metastasis
por: Sheng, Gaohong, et al.
Publicado: (2021)

High Expression of N-Acetylgalactosaminyltransferase 1 (GALNT1) Associated with Invasion, Metastasis, and Proliferation in Osteosarcoma
por: Zhang, Liwen, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_90d2ndpj5bpra982hj42krtpbv