The role of nuclear factor I-C in tooth and bone development

Nuclear factor I-C (NFI-C) plays a pivotal role in various cellular processes such as odontoblast and osteoblast differentiation. Nfic-deficient mice showed abnormal tooth and bone formation. The transplantation of Nfic-expressing mouse bone marrow stromal cells rescued the impaired bone formation i...

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Detalles Bibliográficos
Autores principales: Roh, Song Yi, Park, Joo-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Oral and Maxillofacial Surgeons 2017
Materias:
Invited Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410429/
https://www.ncbi.nlm.nih.gov/pubmed/28462188
http://dx.doi.org/10.5125/jkaoms.2017.43.2.63
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author Roh, Song Yi
Park, Joo-Cheol
author_facet Roh, Song Yi
Park, Joo-Cheol
author_sort Roh, Song Yi
collection PubMed
description Nuclear factor I-C (NFI-C) plays a pivotal role in various cellular processes such as odontoblast and osteoblast differentiation. Nfic-deficient mice showed abnormal tooth and bone formation. The transplantation of Nfic-expressing mouse bone marrow stromal cells rescued the impaired bone formation in Nfic(-/-) mice. Studies suggest that NFI-C regulate osteogenesis and dentinogenesis in concert with several factors including transforming growth factor-β1, Krüppel-like factor 4, and β-catenin. This review will focus on the function of NFI-C during tooth and bone formation and on the relevant pathways that involve NFI-C.
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spelling pubmed-54104292017-05-01 The role of nuclear factor I-C in tooth and bone development Roh, Song Yi Park, Joo-Cheol J Korean Assoc Oral Maxillofac Surg Invited Review Article Nuclear factor I-C (NFI-C) plays a pivotal role in various cellular processes such as odontoblast and osteoblast differentiation. Nfic-deficient mice showed abnormal tooth and bone formation. The transplantation of Nfic-expressing mouse bone marrow stromal cells rescued the impaired bone formation in Nfic(-/-) mice. Studies suggest that NFI-C regulate osteogenesis and dentinogenesis in concert with several factors including transforming growth factor-β1, Krüppel-like factor 4, and β-catenin. This review will focus on the function of NFI-C during tooth and bone formation and on the relevant pathways that involve NFI-C. The Korean Association of Oral and Maxillofacial Surgeons 2017-04 2017-04-25 /pmc/articles/PMC5410429/ /pubmed/28462188 http://dx.doi.org/10.5125/jkaoms.2017.43.2.63 Text en Copyright © 2017 The Korean Association of Oral and Maxillofacial Surgeons. http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Invited Review Article
Roh, Song Yi
Park, Joo-Cheol
The role of nuclear factor I-C in tooth and bone development
title The role of nuclear factor I-C in tooth and bone development
title_full The role of nuclear factor I-C in tooth and bone development
title_fullStr The role of nuclear factor I-C in tooth and bone development
title_full_unstemmed The role of nuclear factor I-C in tooth and bone development
title_short The role of nuclear factor I-C in tooth and bone development
title_sort role of nuclear factor i-c in tooth and bone development
topic Invited Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410429/
https://www.ncbi.nlm.nih.gov/pubmed/28462188
http://dx.doi.org/10.5125/jkaoms.2017.43.2.63
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