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Deletion of Dock10 in B Cells Results in Normal Development but a Mild Deficiency upon In Vivo and In Vitro Stimulations

We sought to identify genes necessary to induce cytoskeletal change in B cells. Using gene expression microarray, we compared B cells stimulated with interleukin-4 (IL-4) and anti-CD40 antibodies that induce B cell spreading, cell motility, tight aggregates, and extensive microvilli with B cells sti...

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Detalles Bibliográficos
Autores principales: Gerasimčik, Natalija, He, Minghui, Baptista, Marisa A. P., Severinson, Eva, Westerberg, Lisa S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410582/
https://www.ncbi.nlm.nih.gov/pubmed/28507547
http://dx.doi.org/10.3389/fimmu.2017.00491