Cargando…

The B(12)-Radical SAM Enzyme PoyC Catalyzes Valine C(β)-Methylation during Polytheonamide Biosynthesis

[Image: see text] Genomic and metagenomic investigations have recently led to the delineation of a novel class of natural products called ribosomally synthesized and post-translationally modified peptides (RiPPs). RiPPs are ubiquitous among living organisms and include pharmaceutically relevant comp...

Descripción completa

Detalles Bibliográficos
Autores principales: Parent, Aubérie, Guillot, Alain, Benjdia, Alhosna, Chartier, Gwladys, Leprince, Jérôme, Berteau, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410653/
https://www.ncbi.nlm.nih.gov/pubmed/27934015
http://dx.doi.org/10.1021/jacs.6b06697