Covalent Attachment of Daptomycin to Ti6Al4V Alloy Surfaces by a Thioether Linkage to Inhibit Colonization by Staphylococcus aureus

[Image: see text] Infections are a devastating complication of titanium alloy orthopedic implants. Current therapies include antibiotic-impregnated bone cement and antibiotic-containing coatings. Daptomycin (DAP) (1) is a novel peptide antibiotic that penetrates the cell membranes of Gram-positive b...

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Detalles Bibliográficos
Autores principales: Chen, Chang-Po, Jing, Rui-Yan, Wickstrom, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410658/
https://www.ncbi.nlm.nih.gov/pubmed/28474012
http://dx.doi.org/10.1021/acsomega.6b00567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410658/
https://www.ncbi.nlm.nih.gov/pubmed/28474012
http://dx.doi.org/10.1021/acsomega.6b00567

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