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Covalent Attachment of Daptomycin to Ti6Al4V Alloy Surfaces by a Thioether Linkage to Inhibit Colonization by Staphylococcus aureus
[Image: see text] Infections are a devastating complication of titanium alloy orthopedic implants. Current therapies include antibiotic-impregnated bone cement and antibiotic-containing coatings. Daptomycin (DAP) (1) is a novel peptide antibiotic that penetrates the cell membranes of Gram-positive b...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410658/ https://www.ncbi.nlm.nih.gov/pubmed/28474012 http://dx.doi.org/10.1021/acsomega.6b00567 |