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C-C motif-ligand 2 inhibition with emapticap pegol (NOX-E36) in type 2 diabetic patients with albuminuria

Background: Emapticap pegol (NOX-E36) is a Spiegelmer(®) that specifically binds and inhibits the pro-inflammatory chemokine C-C motif-ligand 2 (CCL2) (also called monocyte-chemotactic protein 1). The objective of this exploratory study was to evaluate the safety and tolerability as well as the reno...

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Detalles Bibliográficos
Autores principales: Menne, Jan, Eulberg, Dirk, Beyer, Diana, Baumann, Matthias, Saudek, Frantisek, Valkusz, Zsuzsanna, Więcek, Andrzej, Haller, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410979/
https://www.ncbi.nlm.nih.gov/pubmed/28186566
http://dx.doi.org/10.1093/ndt/gfv459