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Phantom PAINS: Problems with the Utility of Alerts for Pan-Assay INterference CompoundS
[Image: see text] The use of substructural alerts to identify Pan-Assay INterference compoundS (PAINS) has become a common component of the triage process in biological screening campaigns. These alerts, however, were originally derived from a proprietary library tested in just six assays measuring...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411023/ https://www.ncbi.nlm.nih.gov/pubmed/28165734 http://dx.doi.org/10.1021/acs.jcim.6b00465 |