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Optimized approach for Ion Proton RNA sequencing reveals details of RNA splicing and editing features of the transcriptome

RNA-sequencing (RNA-seq) has become the standard method for unbiased analysis of gene expression but also provides access to more complex transcriptome features, including alternative RNA splicing, RNA editing, and even detection of fusion transcripts formed through chromosomal translocations. Howev...

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Detalles Bibliográficos
Autores principales: Brown, Roger B., Madrid, Nathaniel J., Suzuki, Hideaki, Ness, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411089/
https://www.ncbi.nlm.nih.gov/pubmed/28459821
http://dx.doi.org/10.1371/journal.pone.0176675