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Dynamics of adaptive immunity against phage in bacterial populations

The CRISPR (clustered regularly interspaced short palindromic repeats) mechanism allows bacteria to adaptively defend against phages by acquiring short genomic sequences (spacers) that target specific sequences in the viral genome. We propose a population dynamical model where immunity can be both a...

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Detalles Bibliográficos
Autores principales:	Bradde, Serena, Vucelja, Marija, Teşileanu, Tiberiu, Balasubramanian, Vijay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411097/ https://www.ncbi.nlm.nih.gov/pubmed/28414716 http://dx.doi.org/10.1371/journal.pcbi.1005486

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