Genetic profiling of two phenotypically distinct outbred rats derived from a colony of the Zucker fatty rats maintained at Tokyo Medical University

The Zucker fatty (ZF) rat is an outbred rat and a well-known model of obesity without diabetes, harboring a missense mutation (fatty, abbreviated as fa) in the leptin receptor gene (Lepr). Slc:Zucker (Slc:ZF) outbred rats exhibit obesity while Hos:ZFDM-Lepr(fa) (Hos:ZFDM) outbred rats exhibit obesit...

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Detalles Bibliográficos
Autores principales: Nakanishi, Satoshi, Kuramoto, Takashi, Kashiwazaki, Naomi, Yokoi, Norihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2016
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411295/
https://www.ncbi.nlm.nih.gov/pubmed/27795491
http://dx.doi.org/10.1538/expanim.16-0068

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