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Myostatin gene knockout mediated by Cas9-D10A nickase in chicken DF1 cells without off-target effect

OBJECTIVE: Based on rapid advancement of genetic modification techniques, genomic editing is expected to become the most efficient tool for improvement of economic traits in livestock as well as poultry. In this study, we examined and verified the nickase of mutated CRISPR-associated protein 9 (Cas9...

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Detalles Bibliográficos
Autores principales:	Lee, Jeong Hyo, Kim, Si Won, Park, Tae Sub
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST) 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411835/ https://www.ncbi.nlm.nih.gov/pubmed/27764916 http://dx.doi.org/10.5713/ajas.16.0695

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