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Nanoporous mannitol carrier prepared by non-organic solvent spray drying technique to enhance the aerosolization performance for dry powder inhalation
An optimum carrier rugosity is essential to achieve a satisfying drug deposition efficiency for the carrier based dry powder inhalation (DPI). Therefore, a non-organic spray drying technique was firstly used to prepare nanoporous mannitol with small asperities to enhance the DPI aerosolization perfo...
Autores principales: | Peng, Tingting, Zhang, Xuejuan, Huang, Ying, Zhao, Ziyu, Liao, Qiuying, Xu, Jing, Huang, Zhengwei, Zhang, Jiwen, Wu, Chuan-yu, Pan, Xin, Wu, Chuanbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411962/ https://www.ncbi.nlm.nih.gov/pubmed/28462948 http://dx.doi.org/10.1038/srep46517 |
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