Synthesis of practical red fluorescent probe for cytoplasmic calcium ions with greatly improved cell-membrane permeability

In this data article, we described the detailed synthetic procedure and the experimental data for the synthesis of a red-fluorescent probe for calcium ions (Ca(2+)) with improved water solubility. This Ca(2+) red-fluorescent probe CaTM-3 AM could be applied to fluorescence imaging of physiological C...

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Detalles Bibliográficos
Autores principales: Hirabayashi, Kazuhisa, Hanaoka, Kenjiro, Egawa, Takahiro, Kobayashi, Chiaki, Takahashi, Shodai, Komatsu, Toru, Ueno, Tasuku, Terai, Takuya, Ikegaya, Yuji, Nagano, Tetsuo, Urano, Yasuteru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412011/
https://www.ncbi.nlm.nih.gov/pubmed/28491938
http://dx.doi.org/10.1016/j.dib.2017.04.011
Descripción
Sumario:In this data article, we described the detailed synthetic procedure and the experimental data for the synthesis of a red-fluorescent probe for calcium ions (Ca(2+)) with improved water solubility. This Ca(2+) red-fluorescent probe CaTM-3 AM could be applied to fluorescence imaging of physiological Ca(2+) concentration changes in not only live cells, but also brain slices, with high cell-membrane permeability leading to bright fluorescence in biosamples. The data provided herein are in association with the research article “The Development of Practical Red Fluorescent Probe for Cytoplasmic Calcium Ions with Greatly Improved Cell-membrane Permeability” in Cell Calcium (Hirabayashi et al., 2016) [1].

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